Tetrahydroquinolines

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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Details

C514S253050, C544S121000, C544S363000

Reexamination Certificate

active

07101881

ABSTRACT:
The present invention relates to compounds of formula Iwherein X and Y are as defined in the specification, and to pharmaceutical compositions comprising the compound of formula I and a pharmaceutically effective carrier; and to a method useful in treating or preventing in mammals, including humans, a disorder or condition selected from the group consisting of anxiety, depression, dysthymia, major depressive disorder, migraine, post-traumatic stress disorder, avoidant personality disorder, borderline personality disorder and phobias.

REFERENCES:
patent: 6313118 (2001-11-01), Berg et al.
patent: 03037887 (2003-05-01), None
K. Rasmussen et al.,Recent Progress in Serotonin(5-HT)1AReceptor Modulators,Ann. Rap. Med. Chem., 1, 30, 1-9 (1995).
R. Sharma et al.,5-HT 1B Receptor System: Possible Implications for Schizophrenic Negative SymptomatologyPsychiatric Annals, 26, 88-92 (1998).
S. Ramboz, et al.,5-HT1B receptor knock out-behavioral consequences,Behav. Brain Res., 73, 305-312 (1996).

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