Tetrahydropyridyl-alkyl-heterocycles, method for preparing...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C514S249000, C514S266210, C514S307000, C514S314000, C514S338000, C514S339000, C544S235000, C544S237000, C544S284000, C544S353000, C546S148000, C546S166000, C546S256000, C546S273400, C546S275700, C546S277400

Reexamination Certificate

active

10475460

ABSTRACT:
The present invention relates to compounds of formula (I):in which X represents N or CH; R1represents a hydrogen or halogen atom or a CF3group; R2and R3independently represent a hydrogen atom or a methyl group; n is 0 or 1; A represents an optionally substituted nitrogenous heterocycle; and to their N-oxides and to their salts or solvates, to the pharmaceutical compositions and the medicaments comprising them, and to a process for their preparation.

REFERENCES:
patent: 5981754 (1999-11-01), Badone et al.
patent: 6344464 (2002-02-01), Bourrie et al.
patent: 0 164 633 (1985-12-01), None
patent: WO 97/01536 (1997-01-01), None
patent: WO 98/48802 (1998-11-01), None
Bourrie, Bernard et al., “The neuroprotective agent SR57746A abrogates experimental autoimmune encephalomyelitis and impairs associated blood-brain barrier disruption: implications for multiple sclerosis treatment”; Proc. Natl. Acad. Sci. U.S.A.; 1999; 96(22). 12855-12859.

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