Tetrahydropyran derivatives

Organic compounds -- part of the class 532-570 series – Organic compounds – Unsubstituted hydrocarbyl chain between the ring and the -c-...

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540452, C02D49116, A61K 31395

Patent

active

054930197

ABSTRACT:
The invention concerns the compounds of formula I ##STR1## wherein the substituents have various significances, in free form and, where such forms exist, in salt form.
They can be prepared by various processes, e.g. by irradiation; oxidation; elimination; reduction; conversion by e.g. halogenation or acylation; deprotection of protected hydroxy groups; protection of free hydroxy groups; and separation of stereoisomeric mixtures into individual isomers.
They are useful as pharmaceuticals, especially as antiinflammatory, and as antiproliferative and antiinflammatory agents.

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