Organic compounds -- part of the class 532-570 series – Organic compounds – Unsubstituted hydrocarbyl chain between the ring and the -c-...
Patent
1994-05-26
1996-02-20
Bond, Robert T.
Organic compounds -- part of the class 532-570 series
Organic compounds
Unsubstituted hydrocarbyl chain between the ring and the -c-...
540452, C02D49116, A61K 31395
Patent
active
054930197
ABSTRACT:
The invention concerns the compounds of formula I ##STR1## wherein the substituents have various significances, in free form and, where such forms exist, in salt form.
They can be prepared by various processes, e.g. by irradiation; oxidation; elimination; reduction; conversion by e.g. halogenation or acylation; deprotection of protected hydroxy groups; protection of free hydroxy groups; and separation of stereoisomeric mixtures into individual isomers.
They are useful as pharmaceuticals, especially as antiinflammatory, and as antiproliferative and antiinflammatory agents.
Bond Robert T.
Honor Robert S.
Kassenoff Melvyn M.
McGovern Thomas O.
Sandoz Ltd.
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