Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – N-c doai
Patent
1990-05-08
1991-12-24
Schenkman, Leonard
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
N-c doai
514530, 514532, 514608, 514706, 514712, 514725, A61K 3110, A61K 3127
Patent
active
050753339
ABSTRACT:
The use of compounds of formula I as topical agents to combat the disorders of the skin produced by photodamage which disorders include: wrinkling, elastosis and premature aging is described. Compounds of formula I are ##STR1## wherein n represents 1 or 2, Z represents--SR, wherein R represents lower-alkyl, lower-alkenyl, lower-alkynyl, lower-alkoxy-lower-alkyl, lower-alkanoyl-lower-alkyl, hydroxy-lower-alkyl, halo-lower-alkyl, lower-carbalkoxy-lower alkyl, mono-lower-alkylamino, di-lower-alkylamino, mono-lower-alkylamido, or di-lower-alkylamido
and pharmaceutically acceptable salts thereof.
REFERENCES:
patent: 4396553 (1983-08-01), Klaus
patent: 4608146, Kligman
patent: 4877805, Kligman
patent: 4888342 (1989-12-01), Kligman
Bryce Graeme F.
Shapiro Stanley S.
Epstein William H.
Gould George M.
Hoffmann-La Roche Inc.
Pokras Bruce A.
Schenkman Leonard
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