Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2007-09-11
2007-09-11
Wilson, James O. (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S308000, C544S284000, C546S140000
Reexamination Certificate
active
11062133
ABSTRACT:
The invention pertains to substituted quinazoline and isoquinoline compounds that serve as effective phosphodiesterase (PDE) inhibitors. In particular, the invention relates to said compounds which are selective inhibitors of PDE-10. The invention also relates to intermediates for preparation of said compounds; pharmaceutical compositions comprising said compounds; and the use of said compounds in a method for treating certain central nervous system (CNS) or other disorders.
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Database Chemcats Chemical Abstracts Service, Columbus, Ohio, US: XP002327094, 2002.
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Katritzky A R et al: “Carbon Dioxide: A Reagent for the Protection of Nuclephilic Centres and The Simulaneous Activation of Electrophilic Attack. Part II. A New Synthetic Method for the 1-Substitution of 1,2,3,4-Thtrahydroisoquinolines” Tetrahedron, Elsevier Science Publishers, Amsterdam, NL, vol. 42, No. 9, 1986, pp. 2571-2574, XP000882952 ISSN: 0040-4020.
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Allen Martin Patrick
Chappie Thomas Allen
Humphrey John Michael
Liras Spiros
Whalen William Michael
Jubinsky James A.
Pfizer Inc.
Truong Tamthom N
Wilson James O.
Zelson Steve
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