Tetrahydroisoquinolines as alpha-2 antagonists and biogenic amin

Details Tetrahydroisoquinolines as alpha-2 antagonists and biogenic amin Tetrahydroisoquinolines as alpha-2 antagonists and biogenic amin

1993-09-10

1995-02-14

Ivy, C. Warren

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514307, 514309, 546 90, 546146, 546150, 546141, N61K 3147, C07D21718, C07D40106

Patent

active

053896386

ABSTRACT:
The present invention provides a tetrahydroisoquinoline compound of the formula ##STR1## or a pharmaceutically acceptable salt thereof which is an antagonist for alpha-2 adrenoreceptors and/or which inhibits biogenic amine uptake.

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patent: 4362875 (1982-12-01), Seubert
patent: 5041451 (1991-08-01), Colle et al.
patent: 5118690 (1992-06-01), Minchin et al.
Hromatka et al, Monatsh. Chem. vol. 97, No. (1), pp. 19-32, 1966.

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