Tetrahydroisoquinoline derivatives as melatonin MT2 antagonists

Details Tetrahydroisoquinoline derivatives as melatonin MT2 antagonists Tetrahydroisoquinoline derivatives as melatonin MT2 antagonists

2005-06-21

2005-06-21

Davis, Zinna Northington (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C546S146000

Reexamination Certificate

active

06908931

ABSTRACT:
The invention encompasses a series of tetrahydroisoquinolines of formula I which are antagonists of the human melatonin MT2receptor and are useful as chronobiotic and sleep agents.

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