Tetrahydroisoquinoline compounds and a pharmaceutical compositio

Details Tetrahydroisoquinoline compounds and a pharmaceutical compositio Tetrahydroisoquinoline compounds and a pharmaceutical compositio

1980-04-10

1981-10-13

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

546147, A61K 3147, C07D21716, C07D21724

Patent

active

042948320

ABSTRACT:
A tetrahydroisoquinoline compound of the formula: ##STR1## wherein R.sup.1 is alkyl of one to six carbon atoms, cycloalkyl of three to six carbon atoms, allyl or propargyl, R.sup.2 is hydrogen or alkyl of one to six carbon atoms, and R.sup.3 is hydrogen, alkyl of one to six carbon atoms or benzyl. Methods for preparing the compound (I) are disclosed. The compound (I) and a pharmaceutically acceptable salt thereof are useful as a diagnostic or therapeutic agent for angiotensin-related hypertension.

REFERENCES:
patent: 3691169 (1972-09-01), Gray
patent: 3691170 (1972-09-01), Gray

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