Tetrahydroindeno[1,2-D][1,3,2]oxazaboroles and their use as enan

Details Tetrahydroindeno[1,2-D][1,3,2]oxazaboroles and their use as enan Tetrahydroindeno[1,2-D][1,3,2]oxazaboroles and their use as enan

1994-05-31

1996-02-27

Brust, Joseph Paul

Organic compounds -- part of the class 532-570 series

Organic compounds

Oxygen containing

568814, 568837, 568881, 546344, 548562, 549 78, 556143, C07C 3701, C07C 29143

Patent

active

054950546

ABSTRACT:
A method for the enantioselective reduction of prochiral ketones using catalytic amounts of tetrahydroindeno[1,2-d][1,3,2] oxazaboroles of formula II is disclosed. ##STR1## The oxazaboroles can be generated in situ from the corresponding cis-1-amino-2-indanols or imino indanols (III) ##STR2## Novel compounds of formulas II and III are also disclosed.

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