Tetrahydroimidazo(3,4-c)-1,3-diazocine intermediates for product

Details Tetrahydroimidazo(3,4-c)-1,3-diazocine intermediates for product Tetrahydroimidazo(3,4-c)-1,3-diazocine intermediates for product

1982-10-26

1984-04-17

Daus, Donald G.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

544281, 546276, 548198, 548203, 548205, 548214, 548324, 548336, C07D48704

Patent

active

044433751

ABSTRACT:
This invention relates to a process for preparing imidazolylalkylguanidines, in particular N-[3-(4-imidazolyl)propyl]-N'-[2-(5-methyl-4-imidazolylmethylthio)ethyl]gu anidine (impromidine) which has histamine H.sub.2 -agonist activity, to intermediates for use in this process and to processes for preparing these intermediates.

REFERENCES:
patent: 3763179 (1973-10-01), Gall
patent: 4013659 (1977-03-01), Durant et al.
patent: 4233302 (1980-11-01), Martin-Smith et al.
Derwent Abstract 33126C (EP 10418).
Derwent Abstract 53014B (EP 2930).
Chem. Abst. 61:5638(c) [Ackermann et al., Z. Physiol. Chem., 336(4-6), 283-284, (1964).]

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