Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1995-06-02
1998-02-03
Bernhardt, Emily
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514 85, 5142278, 5142362, 544 60, 544121, 544337, 544357, 544364, 544366, A61K 31495, C07D40514
Patent
active
057144907
ABSTRACT:
A compound represented by the formula I ##STR1## wherein X is independently both F or both Cl or one X is independently F and the other is independently Cl; R.sub.1 is a straight or branched chain (C.sub.3 to C.sub.8) alkyl group substituted by one or two amino acid ester groups (e.g., an amino acid ester group convertible in vivo into a hydroxy group) thereof or a pharmaceutically acceptable salt thereof and pharmaceutical compositions thereof useful for treating and/or preventing fungal infections are disclosed.
REFERENCES:
patent: 4791111 (1988-12-01), Heeres et al.
patent: 5039676 (1991-08-01), Saksena et al.
Sinkula, in Annual Reports in Medicinal Chemistry vol. 10, Chapter 31, pp. 306-315 (1975).
Bennett Frank
Ganguly Ashit K.
Girijavallabhan Viyyoor M.
Liu Yi-Tsung
Lovey Raymond G.
Bernhardt Emily
Hoffman Thomas D.
Schering Corporation
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