Tetrahydro-naphthalene and urea derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C514S319000, C544S390000

Reexamination Certificate

active

07615557

ABSTRACT:
This invention relates to a hydroxy-tetrahydro-naphthalene or an urea derivative formula (I) and salts thereof which are useful as active ingredients of pharmaceutical preparations, wherein A represents formula (II) or (III) wherein # represents the connection position to the molecule and Q1a, Q2a, Q3aand Q4aare defined, and E represents formula (IV) or (V) wherein # represents the connection position to the molecule and Q1b, Q2b, Q3b, Q4b, Q5b, R1b, na, ma, Xaand Raare defined.

REFERENCES:
patent: WO 02/08221 (2002-01-01), None
patent: WO 03/014064 (2003-02-01), None
patent: WO 03/068749 (2003-02-01), None
patent: WO 03/022809 (2003-03-01), None
patent: WO 03/068749 (2003-08-01), None
patent: WO 2004/052845 (2004-06-01), None
Walker, et al., The VR1 Antagonist Capsazepine Reverses Mechanical Hyperalgesia in Models of Inflammatory and Neuropathic Pain, J. of Pharm. and Exper. Ther., vol. 304, No. 1, pp. 56-62 (2003).
Patent Abstract of Japan, vol. 2003, No. 11, Nov. 5, 2003 & JP 2003 192673 A (Bayer AG).
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Office Action dated Nov. 30, 2007 in connection with U.S. Appl. No. 10/537,217.
Office Action dated Jul. 2, 2008 in connection with U.S. Appl. No. 10/537,217.
Office Action dated Jan. 13, 2009 in connection with U.S. Appl. No. 10/513,848.

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