Tetrahydro-naphth (2.3-d) imidazole derivatives

Details Tetrahydro-naphth (2.3-d) imidazole derivatives Tetrahydro-naphth (2.3-d) imidazole derivatives

1983-12-12

1986-07-08

Fan, Jane T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546271, A61K 3144, C07D40112

Patent

active

045993475

ABSTRACT:
Tricyclic imidazole derivatives of the formula ##STR1## wherein R.sup.1 is 2-pyridyl optionally substituted by lower alkyl or lower alkoxy, n is the integer 0 to 1, R.sup.2 is hydrogen or lower alkyl, R.sup.3 and R.sup.4, independently, are hydrogen or lower alkyl, A is a group of the formula ##STR2## m is the integer 2 or 3, R.sup.5, R.sup.6, R.sup.7 and R.sup.8, independently, are hydrogen or lower alkyl, and R.sup.9 is hydrogen and R.sup.10 is hydrogen or lower alkyl or R.sup.9 and R.sup.10 taken together are oxo, provided that at least one of R.sup.3 and R.sup.4 is lower alkyl when A is a group of the formula

REFERENCES:
patent: 4182766 (1980-01-01), Krasso et al.
G. Sundell et al. Acta Physicol. Scand. Suppl. 473,41 (1979).

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