Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1995-05-19
1997-07-01
Rotman, Alan L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514292, 546 70, 546 86, 546 87, A61K 3144, C07D47104, C07D48704
Patent
active
056439164
ABSTRACT:
The present invention provides novel tetrahydro-beta-carboline compounds having useful central nervous system activity. Further, there is provided tetrahydro-beta-carboline related compounds which are useful intermediates and have beneficial central nervous system activity. The invention provides formulations and methods for using the novel tetrahydro-beta-carboline and related compounds. Such compounds are particularly useful for the modulation of a 5-HT.sub.2B receptor.
REFERENCES:
Derwent Abstract 03884Y/03 25 Jun. 1975 BE-843-215.
Derwent Abstract 68225 c/39 05 Feb. 1979 EP--15-786.
Derwent Abstract 84-115276/19 29 Oct. 1982 DE-3240-514-A.
Derwent Abstract 40991 14 Apr. 1967 US/3,480,637.
Dubois, et al., J. Org. Chem., 59, 434-441 (1994).
Legters, et al., Rccl. Trav. Chim. Pays-Bas, 111, 16-21, (1992).
Sato, K. and Kozikowski, A. P., Tetrahedron Letters, 30:31., 4073-4076, (1989).
Shima, et al., Chem. Pharm. Bull., 38:2, 564-566 (1990).
Audia James E.
Baker Stephen Richard
Carrera Jesus Ezquerra
Pedregal Tercero Concepcion
Peteira Carlos Lamas
Boone David E.
Eli Lilly and Company
Rotman Alan L.
LandOfFree
Tetrahydro-beta-carbolines does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Tetrahydro-beta-carbolines, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Tetrahydro-beta-carbolines will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-597381