Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2011-06-28
2011-06-28
Moore, Susanna (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C540S579000, C540S476000, C514S259410, C514S214020, C544S282000
Reexamination Certificate
active
07968553
ABSTRACT:
Tetrahydro-4H-pyrido[1,2-a]pyrimidines and related compounds of Formula A:are described as inhibitors of HIV integrase and inhibitors of HIV replication, wherein n is an integer equal to zero, 1, 2 or 3, and R1, R3, R4, R12, R14, R16, R30, R32, R34and R36are defined herein. These compounds are useful in the prevention and treatment of infection by HIV and in the prevention, delay in the onset, and treatment of AIDS. The compounds are employed against HIV infection and AIDS as compounds per se or in the form of pharmaceutically acceptable salts. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines.
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Crescenzi Benedetta
Kinzel Olaf
Muraglia Ester
Orvieto Federica
Pescatore Giovanna
Istituto di Ricerche di Biologia Molecolare P. Angeletti S.p.A.
Moore Susanna
Walton Kenneth R.
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