Tetrafluorobenzyl derivatives and pharmaceutical composition...

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C562S458000, C560S048000, C560S047000

Reexamination Certificate

active

07371896

ABSTRACT:
The present invention relates to a tetrafluorobenzyl derivative and a pharmaceutical composition for prevention and treatment of acute and chronic neurodegenerative disease in central nervous system and ophthalmic diseases containing the same. The tetrafluorobenzyl derivative of the present invention can effectively be used to prevent and treat chronic neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease and Huntington's disease, degenerative brain disease such as epilepsy and ischemic brain disease such as stroke.

REFERENCES:
patent: 3632760 (1972-01-01), Shen et al.
patent: 3674844 (1972-07-01), Shen et al.
patent: 5434163 (1995-07-01), Edlind et al.
patent: 5527814 (1996-06-01), Louvel
patent: 6136835 (2000-10-01), Camden
patent: 6358945 (2002-03-01), Breitfelder et al.
patent: 6573402 (2003-06-01), Gwag et al.
patent: 2031227 (1971-01-01), None
patent: 122827 (1984-10-01), None
patent: 1268465 (1972-03-01), None
patent: 54-125632 (1979-09-01), None
patent: 60-237041 (1985-11-01), None
patent: 2000-212141 (2000-08-01), None
patent: 2000-273041 (2000-10-01), None
patent: WO 86/03199 (1986-06-01), None
patent: WO 94/13663 (1994-06-01), None
patent: WO 99/01421 (1999-01-01), None
Lehninger et al., Principles of Biochemistry, 2nd. ed. 384-390, 1993.
Anderson, D.K. et al., Ann. Emerg. Med. 22:987-992 (1993).
Anderson, W.W. et al., J. Neurophysiol. 57:1-21 (1987).
Beal, M.F. et al, J.Neurosci. 11:1649-1659 (1991).
Beal, M.F. et al., Nature 321: 168-171 (1986).
Beal, M.F., Ann. Neurol. 38:357-366 (1995).
Benveniste, H et al.,J. Neurochem, 43(5):1369-1374 (1984).
Brouillet, E. et al.. Neuroreport. 4:387-390 (1993).
Browne, S.E. et al., Brain Pathol. 9:147-163 (1999).
Bush, A.I. et al., Science 265:1464-1467 (1994).
Chan, P. H.J. Neurotrauma., 9 Suppl 2:S417-423 (1992).
Chan, P.H., Stroke 27:1124-1129 (1996).
Choi, D.W. et al., J Neurosci. 7:369-379, 1987.
Choi, D.W. et al., Annu Rev Neurosci 13:171-182 (1990).
Choi, D.W. et al., Annu. Rev. Neursci 21:347-375 (1988).
Choi, D.W. et al., Journal of Neuroscience 7(2): 357-368 (1987).
Choi, D.W., Neuron 1:623-634 (1988).
Cuajungco, M.P. et al., Brain Research Reviews 23:219-236 (1997).
Demediuk, P. et al., J. Neurochem. 52:1529-1536 (1989).
Dexter, D. T. et al.,Ann Neurol., 32 Suppl:S94-100 (1992).
Dingledine, R. et al., Trends Pharmacol. Sci. 11:334-338 (1990).
Eisen, A. et al., Drugs Aging 14:173-196 (1999).
Faden, A.I. et al, Science 244:798-800 (1989).
Faden, A.I. et al., J. Neurotrauma. 5:33-45 (1988).
Faden, A.I., Pharmacol. Toxicol. 78:12-17 (1996).
Fahn, S. and Cohen, G.,Ann. Neurol., 32(6):804-812 (1992).
Ferrante, R. J. et al.,Science, 230(4625):561-563 (1985).
Fischer-Nielsen, A. et al.,Free Radic Biol Med. 13(2): 121-126 (1992).
Flamm, E. S. et al.,Stroke, 9(5):445-447 (1978).
Frederickson, C. J. and Bush, A. I.,Biometals, 14:353-366 (2001).
Frederickson, C.J. et al., Brain Res. 480:317-321 (1989).
Gerlach, M. et al.,Journal of Neurochemistry63: 793-807 (1994).
Gilgun-Sherki, Y. et al.,Pharmacological Reviews54: 271-284 (2002).
Goldberg, M. P. et al.J. Pharmac. Exp. Ther., 243:784-791 (1987).
Goldberg, M.P. et al., J Neurosci. 13:3510-3524 (1993).
Goodman & Gilman's The Pharmacological Basis of Therapeutics, Joel G. Hardman et al., eds., 9.sup.th edition, 1996, The McGraw-Hill Companies, pp. 617-631 & 1059-1062.
Grisham, M.B. et al.,Dig. Dis Sci. 37(9): 1383-1389 (1992).
Grundman, M., Am.J.Clin.Nutr. 71:630S.-636S (2000).
Gwag, BJ et al., Neuroscience. 68:615-619 (1995).
Hall, E.D. et al., Free Radic.Biol.Med. 6:303-313 (1989).
Hall, E.D. et al., J. of Neurotrauma. 5:81-89 (1988).
Hall, E.D., Neurosurg.Clin.N.Am. 8:195-206 (1997).
Holmes, G.L. et al., Cleve. Clin. J. Med. 62:240-247 (1995).
Hussain, F.N. et al.,Br J. Clin Pharmacol. 49(4): 323-330, (Apr. 2000).
Ikonomidou, C, et al., J. Neuropathol. Exp. Neurol. 55:211-224 (1996).
International Preliminary Examination Report for PCT/KR 00/00366, Aug. 23, 2002.
Jenner, and Olanow, Neurology 47:S161-S170 (1996).
Jenner, P., Pathol. Biol. (Paris.) 44:57-64 (1996).
Joo, C-K. et al, Investigative Ophthalmology & Visual Science 40:713-720 (1999).
Kass, I.S. et al., Exp. Neurol. 103:116-122 (1989).
Kim, E.Y. et al, European Journal of Neuroscience, 11:327-334 (1999).
Klotz et al.,Arzneimittel-Forschung. Drug Research43(12): 1357-1359, (Dec. 1993).
Kogure, K. et al.,Prog. Brain Res., 63:237-259 (1985).
Koh, J.Y. et al., J Neurosci Methods 20:83-90 (1987).
Koh, J.Y. et al., Science 234:73-76 (1986).
Koh, J.Y. et al., Science 272: 1013-1016 (1996).
Kumamoto, T. et al.,Jpn. J. Pharmacol. 75: 187-189, 1997.
Lakowski, B. et al., Science 272: 1010-1013 (1996).
Lange, K.W. et al., Naunyn Schmiedebergs Arch.Pharmacol. 348(6):586-592 (1993).
Lee et al.,Proc. Natl. Acad. Sci., U.S.A. 99:7705-7710 (2002).
Lee, J-M et al., Nature 399:A7-A14 (1999).
Love, S., Brain Pathol. 9:119-131 (1999).
Marin, C. et al., Brain Res. 736:202-205 (1996).
McNamara, J.O. et al., Neuropharmacology 27:563-568 (1988).
Merello, M. et al., Clin. Neuropharmacol. 22:273-276 (1999).
Metman, L.V. et al., Neurology 51:203-206 (1998).
Minta, A. et al., Journal of biological Chemistry 264(14):8171-8178 (1989).
Montastruc, J.L. et al, Neuroscience and Biobehavioral Reviews 21(4):477-480 (1997).
Mysyk, D. D. et al., “Chloromethylation of 4-arenesulfonyl-N-methylamidoanisoles,” Soviet Progress in Chemistry. 33(2), 59-62 (1967).
Nussbaumer, P. et al., “Novel Antiproliferative Agents Derived from Lavendustin A,” J. Med. Chem. 37(24), 4079-84 (1994).
Okiyama, K. et al., J. Neurotrauma. 14:211-222 (1997).
Olney et al.,Science, 244:1360-1362 (1989).
Olney, J. W. and Ho, O. L.,Nature, 227(258): 609-611 (1970).
Olney, J. W. and Sharpe, L. G.,Science, 166:386-388 (1969).
Olney, J. W.Int. Rev. Neurobiol., 27:337-362 (1985).
Papa, S.M. et al., Ann. Neurol. 39:574-578 (1996).
Park, C,K, et al., Ann Neurol. 24:543-551 (1988).
PCT International Search Report, PCT/KR00-00366.
Prasad, K.N. et al., J. Am. Coll. Nutr. 18:413-423 (1999).
Rizzi, E. et al., “Electron Impact Spectrometry of some 5-amin-osalicylic acid derivatives,” Rapid Commun. Mass Spectrom. 1994, 8(2), 158-62.
Rosen, D.R. et al., Nature 362:59-62 (1993).
Rothstein, J.D. et al., Clin. Neurosci. 3:348-359 (1995).
Schapira, A. H.,Curr. Opin. Neurol., 9(4)260-264 (1996).
Schröder, H. et al., Clin. Pharmacol. Ther. 13:539-551 (1972).
Schubert, D. et al.,Proc. Natl. Acad. Sci., U.S.A. 92(6):1989-1993 (1995).
Shaw, P. J. and Ince, P. G.,J. Neurol., 244 Suppl 2:S3-14 (1997).
Sheardown, M. J. et al,Science, 247:571-574 (1990).
Siegel G. J. et al.,Basic Neurochemistry,6thedition, Lippincott Williams & Wilkins, 315-333 (1999).
Siesjö, B.K. et al., Eur. J. Anaesthesiol. 13:247-268 (1996).
Simon, R.P. et al., Science 226:850-852 (1984).
Sinz, E.H. et al, J of Cerebral Blood Flow and Metabolism 18:610-615 (1998).
Smith, M.A., et al., Proc. Natl. Acad. Sci. U.S.A. 94:9866-9868 (1997).
Smith, P.R. et al., Gut 20:802-805 (1979).
Sofic, E. et al.,J. Neural Transm., 74:199-205 (1988).
Spector, R. et al.,J. Pharmacol. Exp. Ther. 188: 55-65 (1974).
Stenson, W.F. et al., J. Clin. Invest. 69, 494-497 (1982).
Suh, S.W. et al., Brain Res. 852 258-273 (2000).
Suh, S.W. et al., Brain Res. 852:274-278 (2000).
Wahl, C. et al., J. Clin.Invest. 101:1163-1174 (1998).
Webster's II, New Riverside University Dictionary, Riverside Publishing Company, p. 933, 1988.
Weiss et al.,Trend Pharmacol., Sci. 21:395-401 (2001).
Weiss, J. et al., Brain Res. 380:186-190 (1986).
Weiss, J.H. et al., Neuron. 10:43-49 (1993).
Wieloch, T., Science 230:681-683 (1985).
Won, S.J. et al., Neurobiology of Disease 7:251-2599 (2000).
Wong, B.Y. et al., Neurosci.Lett. 85:261-266 (1988).
Zeidman, S.M. et al., J. Spinal. Disord. 9:367-380 (1996).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Tetrafluorobenzyl derivatives and pharmaceutical composition... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Tetrafluorobenzyl derivatives and pharmaceutical composition..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Tetrafluorobenzyl derivatives and pharmaceutical composition... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2755324

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.