Tetracycline derivatives and methods of use thereof

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – 3,10-dihydroxy-2-naphthacene carboxamide or derivative doai

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C552S203000, C552S205000, C552S206000

Reexamination Certificate

active

10264454

ABSTRACT:
A treatment for inhibiting microbial or tumor growth is disclosed, which comprises adding to a subject in need of treatment an effective amount of one or more tetracycline derivatives.

REFERENCES:
patent: 3029284 (1962-04-01), Gordon
patent: 3145228 (1964-08-01), Stephens, Jr. et al.
patent: 3265732 (1966-08-01), Miller et al.
patent: 3338963 (1967-08-01), Boothe et al.
patent: 3345370 (1967-10-01), Esse et al.
patent: 3345410 (1967-10-01), Winterbottom et al.
patent: 3388162 (1968-06-01), Winterbottom et al.
patent: 3502660 (1970-03-01), Butler et al.
patent: 3502696 (1970-03-01), Conover
patent: 3509184 (1970-04-01), Conover et al.
patent: 3515731 (1970-06-01), Conover
patent: 3609188 (1971-09-01), Esse et al.
patent: 3622627 (1971-11-01), Blackwood et al.
patent: 3772363 (1973-11-01), Conover et al.
patent: 3824285 (1974-07-01), Blackwood et al.
patent: 3829453 (1974-08-01), Conover et al.
patent: 3849493 (1974-11-01), Conover et al.
patent: 4666897 (1987-05-01), Golub et al.
patent: 4704383 (1987-11-01), McNamara et al.
patent: 4935411 (1990-06-01), McNamara et al.
patent: 4935412 (1990-06-01), McNamara et al.
patent: 5045538 (1991-09-01), Schneider et al.
patent: 5122519 (1992-06-01), Ritter
patent: RE34656 (1994-07-01), Golub et al.
patent: 5494903 (1996-02-01), Hlavka et al.
patent: 5495030 (1996-02-01), Sum et al.
patent: 5532227 (1996-07-01), Golub et al.
patent: 5776898 (1998-07-01), Teicher et al.
patent: 6506740 (2003-01-01), Ashley et al.
patent: 6818634 (2004-11-01), Nelson et al.
patent: 6894036 (2005-05-01), Ashley et al.
Van der Bozert et al., Cancer Res. 48:6686-6690 (1988).
The Chemistry of Tetracyclines, Chapter 6, Marcel Dekker Publishers, NY (1978).
Golub, et al.,J. Periodont. Res., 20:12-23 (1985).
Greenwald, et al.,Tetracyclines Suppress Metalloproteinase Activity in Adjuvant Arthritis and, in Combination with Flurbioprofen Ameliorate Bone Damage, Jouranl of Rheumatology 19:927-938 (1992).
Greenwald, et al.,Treatment of Destructive Arthritic Disorders with MMP Inhibitors, Annals of the New York Academy of Sciences 732:181-198 (1994).
Kloppenburg, et al.,Minocycline in Active Rheumatoid Arthritis, Arthritis Rheum 37:629-636 (1994).
Ryan, et al.,Potential of Tetracyclines to Modify Cartilage Breakdown in Osteoarthritis, Current Opinion in Rheumatology 8:38-247 (1996).
O'Dell, et al.,Treatment of Early Rheumatoid Arthritis with Minocycline or Placebo, Arthritis Rheum 40:842-848 (1997).
White, et al.,Lancet, Apr. 29, p. 966 (1989).
DeClerk, et al.,Matrix Metalloproteinases and Their Inhibitors in Tumor Progression, Annals N.Y. Acad. Sci., 732:222-232 (1994).
Rifkin, et al.,Modulation of Bone Resorption by Tetracyclines, Annals N.Y. Sci., 732:165-180 (1994).
Maragoudakis, et al.,Evidence that Nitric Oxide is an Endogenous Antiangiogenic Mediator, Br. J. Pharmacol., 111:894-902 (1994).
Ramamurthy, et al.,CMT/Tenidap Treatment Inhibits Temporomandibular Joint Destruction in Adjuvant Arthritic Rats, Annals N.Y. Acad. Sci., 732, 427-430 (1994).
Golub et al., Tetracyclines inhibit connective tissue breakdown: new therapeutic implications for an old family of drugs (1991) Crit. Revs. Oral. Biol. Med. 2(3): 297-321.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Tetracycline derivatives and methods of use thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Tetracycline derivatives and methods of use thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Tetracycline derivatives and methods of use thereof will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3798537

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.