Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1991-09-19
1992-10-27
Shah, Mukund J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514 19, 540543, C07D22316, C07D491107, C07D49510, A61K 3155
Patent
active
051589486
ABSTRACT:
Novel tetracyclic spirobenzazepine compounds of the formula ##STR1## or a pharmaceutically-acceptable salt, amide or ester thereof, which are dopamine D-1 receptor antagonists useful for treating dopamine-related neurological and psychological disorders, cognitive impairment, attention deficit disorders and addictive behavior disorders.
REFERENCES:
patent: 5010074 (1991-04-01), Gronwald et al.
patent: 5015639 (1991-05-01), Berger et al.
Campbell James R.
Ehrlich Paul P.
Kebabian John W.
Schoenleber Robert W.
Abbott Laboratories
Datlow Philip I.
Elder Richard A.
Janssen Jerry F.
Shah Mukund J.
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