Tetracyclic indole derivatives for treating hypertension

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514389, 544310, 548309, 548421, A61K 3140, A61K 31415, C07D48702

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active

048015881

ABSTRACT:
Compounds of the formula I: ##STR1## wherein R.sub.1 =H, CH.sub.3 ; m=0,1; R.sub.2 =R.sub.3 =H or R.sub.2, R.sub.3 =bond, R.sub.4 =C.sub.1 -C.sub.4 hydrocarbon, n=1 or 2 and their pharmaceutically acceptable salts are antihypertensive agents. Their preparation and pharmaceutical compositions containing them are also described.

REFERENCES:
patent: 4317912 (1982-03-01), Temperilli et al.
patent: 4690929 (1987-09-01), Bernardi et al.
Temperilli et al., Chemical Abst. 94-209049h.

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