Tetracyclic imidazo [2,1-b] quinazolinone derivatives

Details Tetracyclic imidazo [2,1-b] quinazolinone derivatives Tetracyclic imidazo [2,1-b] quinazolinone derivatives

1974-06-21

1976-06-15

Rush, Raymond V.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424251, C07D47104, C07D48704

Patent

active

039637204

ABSTRACT:
Disclosed are compounds which are tetracyclic derivatives of imidazo[2,1-b]quinazolinones, e.g., 6-(p-fluorobenzyl)-1,2,3,4,4a,12a-hexahydrobenzimidazo[2,1-b]quinazolin-11 (6H)-one. The compounds are also useful as bronchodilator agents, and certain compounds are also useful as tranquillizers and sedative/hypnotic agents. The compounds may be prepared by reacting an isatoic anhydride with a 2-organomercapto-hexahydrobenzimidazole or hexahydrocyclopentimidazole such as 3a,4,5,6,7,7a-hexahydro-2-mercaptomethyl-3H-benzimidazole.

REFERENCES:
patent: 3669969 (1972-01-01), Lunn

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