Tetracyclic compounds having anti-allergic and anti-asthmatic ac

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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540578, 540579, 514826, C07D48704, A61K 3155

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active

053627253

ABSTRACT:
Compounds of formula (I): ##STR1## in which: Q is nitrogen or .dbd.CH--; R.sup.1 and R.sup.2 are hydrogen, alkyl, alkoxy, hydroxy, trifluoromethyl or halogen; and R.sup.3 is a substituted alkyl groups or a pharmaceutically acceptable salt thereof have valuable anti-allergic and anti-asthmatic activities. The compounds are prepared by reacting a corresponding compound where R.sup.3 is replaced by a hydrogen atom with a compound to introduce the group R.sup.3.

REFERENCES:
patent: 4025513 (1977-05-01), Olivie
patent: 4062848 (1977-12-01), van der Burg
patent: 4217452 (1980-08-01), Olivie
patent: 4271073 (1981-06-01), Beuder et al.
Ciba-Geigy A-G. Chem. Abst. 92-6566k (1980).
Copp et al., CA 110-95281 u (1989).
Van der Burg, CA 86-29883b (1977).

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