Tetra- and pentapeptides containing the lysyl-arginyl-aspartyl s

Details Tetra- and pentapeptides containing the lysyl-arginyl-aspartyl s Tetra- and pentapeptides containing the lysyl-arginyl-aspartyl s

1988-10-28

1990-07-24

Lee, Lester L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 17, 514 18, 530329, 530330, A61K 3702, C07K 706

Patent

active

049435620

ABSTRACT:
The peptides according to the invention are of the following general formula I:

REFERENCES:
patent: 4190646 (1980-02-01), Goldstein et al.
patent: 4190647 (1980-02-01), Goldstein et al.
patent: 4298523 (1981-11-01), Heavner
patent: 4305852 (1981-12-01), Garsky
patent: 4428938 (1984-01-01), Kisfaludy et al.
patent: 4683291 (1987-07-01), Zimmerman et al.
patent: 4792525 (1988-12-01), Ruoslahti et al.
Sanghamitra Raha et al., "KRDS-A Tetrapeptide Derived From Lactotransferrin-Inhibits Binding of Monoclonal Antibody Against Glycoprotein IIb-IIIa on ADP-Stimulated Platelets and Megakaryocytes", Blood, vol. 72, No. 1, Jul. 1988, pp. 172-178.
Blood, Nov. 1986, No. 1150, Eur. J. Biochem. 158, 379-382 (1986).
Eur. J. Biochem. 145, 659-676 (1984) Blood, 67, 285-293 (1986).
J. Biol. Chem. 258, 12582-12586 (1983) Blood, 69, 570-577 (1987); and Thromb. Haemost. 58, 243A (1987).
Chemical Abstracts, vol. 109, 1988 No. 12647w.

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