Tet repressor-based transcriptional regulatory proteins

Details Tet repressor-based transcriptional regulatory proteins Tet repressor-based transcriptional regulatory proteins

2003-06-05

2009-06-02

Li, Q. Janice (Department: 1633)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C536S023400, C536S024100, C435S069100, C435S320100, C424S093210

Reexamination Certificate

active

07541446

ABSTRACT:
The present invention provides a panel of transcriptional activator fusion proteins which comprises both tetracycline controlled transactivator proteins and reverse tetracycline transactivator proteins. These transactivators have novel phenotypes such as altered basal transcriptional activity in the absence of doxycycline, altered induced transcriptional activity in the presence of doxycycline, or differential induction by tetracycline and analogs of tetracycline.

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