Testosterone derivatives

Details Testosterone derivatives Testosterone derivatives

1975-09-22

1977-06-21

Roberts, Elbert L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424 1, 424 3, 424 12, 26023955C, C07J 100

Patent

active

040311171

ABSTRACT:
Testosterone-15.alpha. or .beta.-carboxyethyl thioether, 5.alpha.-, dihydrotestosterone-15.alpha. or .beta.-carboxyethyl thioether related compounds and intermediates for preparation thereof. The compounds are conjugated to an immunological protein and employed to elicit an antibody highly specific to testosterone and 5.alpha.-dihydrotestosterone respectively. The elicited antibody can be employed for determination of testosterone and 5.alpha.-dihydrotestosterone respectively, in samples, by radioimmunoassay.

REFERENCES:
patent: 3875195 (1975-04-01), Nickolson et al.

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