Test strip for determining concentration of triglycerides

Details Test strip for determining concentration of triglycerides Test strip for determining concentration of triglycerides

2007-05-08

2007-05-08

Gitomer, Ralph (Department: 1657)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving hydrolase

C422S051000

Reexamination Certificate

active

10334044

ABSTRACT:
A dry-phase triglycerides test strip that can be stored at room or elevated temperatures for several months without significant degradation in its effectiveness. The test strip includes a test membrane which receives plasma and forms a colored response in proportion to concentration of triglycerides in the plasma. The test membrane is impregnated with an aqueous solution containing lipoprotein lipase (LPL) and 4-aminoantipyrine (4AAP). The inventors have found that by reducing the pH of the impregnating solution to less than that of the recommended pH range for one of the key components (viz., less than pH 6.0), overall stability of the test strips was dramatically improved. The improvement in storage capability of these triglycerides test strips represents not just a difference in degree, but a difference in kind.

REFERENCES:
patent: 5126246 (1992-06-01), Imamura et al.
patent: 5156954 (1992-10-01), Mielke et al.
patent: 5597532 (1997-01-01), Connolly
patent: 2003/0170768 (2003-09-01), Anaokar et al.
PTS PANELS Triglycerides Test Strips Instructions, (PS-001596 Rev. 2 May 2002).
Cholestech LDX®, Lipid Profile plus Glucose-II, Total Cholesterol, HDL Cholesterol, Triglycerides and Glucose Panel, ackage insert.
LIPID Profile plus Glucose, Cholestech LDX®, Lipid Profile plus Glucose-II, Total Cholesterol, HDL Cholesterol, Triglycerides and Glucose Panel, Box Label.
LIPID Profile plus Glucose, Cholestech LDX®, Lipid Profile plus Glucose-II, Total Cholesterol, HDL Cholesterol, Triglycerides and Glucose Panel, cassette label, ® 1999.
Cholestech LDX®, Lipid Profile plus Glucose-II, Total Cholesterol, HDL Cholesterol, Triglycerides and Glucose Panel, ackage insert, no date given.
LIPID Profile plus Glucose, Cholestech LDX®, Lipid Profile plus Glucose-II, Total Cholesterol, HDL Cholesterol, Triglycerides and Glucose Panel, Box Label, no date given.
LIPID Profile plus Glucose, Cholestech LDX®, Lipid Profile plus Glucose-II, Total Cholesterol, HDL Cholesterol, Triglycerides and Glucose Panel, cassette label,® 1999.

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