Test methods and devices

Details Test methods and devices Test methods and devices

2001-04-03

2008-08-12

Nguyen, Bao-Thuy L (Department: 1641)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

C435S007900, C435S007940, C435S960000, C436S501000, C436S510000, C436S547000, C436S548000, C436S814000, C436S817000, C436S818000, C436S815000, C436S806000

Reexamination Certificate

active

07410768

ABSTRACT:
A method and test device for differentiating between states of an analyte that can exist in different forms, such as follicle stimulating hormone (FSH). The method or test device uses a pair of specific binding agents, especially monoclonal antibodies, in two assays for the same analyte. The assays, applied to contemporaneous samples, differ from one another in format, one being a two step assay and the other being one step. A novel pair of anti-FSH monoclonal antibodies that can be used together in two such assays to differentiate pre-menopausal and post-menopausal FSH samples is disclosed.

REFERENCES:
patent: 4900662 (1990-02-01), Shah et al.
patent: 0736771 (1996-10-01), None
Creus et al., Clinical Endocrinology. Feb. 1996. vol. 44, No. 2, pp. 181-189.
Niccoli et al., Eur. J. Clin. Chem. Clin. Biochem. 1996. 34:741-748.
Alfthan et al., Molecular and Cellular Endocrinology. 1996. 125:107-120.
Matikainen et al., Journal of Clinical Endocrinology and Metabolism. 1992. 75(3):820-825.

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