Test kit for the determination of activated thromboplastin time

Details Test kit for the determination of activated thromboplastin time Test kit for the determination of activated thromboplastin time

1985-02-15

1987-06-09

Naff, David M.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving blood clotting factor

435810, 436 69, 436 70, C12Q 156, G01N 3386

Patent

active

046720308

ABSTRACT:
Partial thromboplastin time (PTT) is determined for monitoring and controlling heparin therapy with a test kit having increased sensitivity to heparin. Increased sensitivity is obtained by including with reagents in the test kit an organic sulfuric acid or salt thereof such as dodecylbenzenesulfuric acid--sodium salt and/or an organic sulfuric acid ester or salt thereof such as sodium laurylsulfate.

REFERENCES:
patent: 3179567 (1965-04-01), Owren
patent: 3486981 (1969-12-01), Speck
patent: 3880714 (1975-04-01), Babson
Lammle et al., (1983) American Society of Clinical Pathologists, vol. 80, No. 4, pp. 474-477.
Hoffmann et al., (1978) Clinica Chimica Acta, vol. 87, pp. 417-424.
Joist et al., (1977) Journal of Laboratory and Clinical Medicine, vol. 90, No. 6, pp. 1054-1065.

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