Test kit and method for the determination of Streptococcus A ant

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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422 57, 422 61, 435 34, 435 36, 435810, 435961, 435975, 436519, 436533, 436534, G01N 33546, G01N 33547, G01N 33569

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active

RE0338508

ABSTRACT:
A test kit useful for the determination of Streptococcus A antigen comprises: (i) an immunoreactive reagent comprising either Streptococcus A antigen or antibodies attached to water-insoluble particles, (ii) a substrate having thereon a dried, binder-free coating of a first extraction reagent, (iii) an aqueous solution of a second extraction reagent, and (iv) a neutralizing solution. Both extraction reagents combine to provide nitrous acid. In addition, an extraction device includes a water-insoluble container having affixed therein the first extraction reagent and an applicator means for collecting and depositing a biological specimen within the container. The extraction device and test kit are useful to the determination of Streptococcus A antigen in a biological specimen.

REFERENCES:
patent: 4618576 (1986-10-01), Rosenstein et al.
patent: 4639419 (1987-01-01), Olson et al.
patent: 4673639 (1987-06-01), Slifkin
patent: 4851337 (1989-07-01), Berke
Slifkin et al., J. Clin. Microbiol. 15 (1) 1982, pp. 187-189.
Slifkin et al., J. Clin. Microbiol. 20 (1) 1984, pp. 12-14.
Guinet et al., Med. Microbiol. Immunol. 171 1982, pp. 23-32.

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