Test for esterase activity in a liquid sample

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving hydrolase

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Details

435805, 435 20, 435 21, C12Q 144, C12Q 146, C12Q 142

Patent

active

044991851

ABSTRACT:
A composition, test device and method for determining the presence of leukocytes, esterase and/or esterase activity in a test sample is disclosed. The composition comprises an ester which, when cleaved by esterolytic activity, produces a detectable response such as color formation. In addition the composition comprises the compound 3-quinuclidinol. The device is prepared by incorporating a carrier matrix, such as paper, with the composition. The method comprises contacting a test sample with the device and observing a detectable response.

REFERENCES:
patent: 4299917 (1981-11-01), Berger et al.
Pyttel et al., J. Pharm. Sci., vol. 62, No. 4, pp. 684-685, 1973.

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