Test device and method of making same

Details Test device and method of making same Test device and method of making same

2007-01-23

2007-01-23

Redding, David (Department: 1744)

Chemistry: molecular biology and microbiology

Apparatus

Including measuring or testing

C435S288500, C435S288600, C435S810000, C422S105000

Reexamination Certificate

active

10097329

ABSTRACT:
The present invention discloses a test device including a support member; a top member mounted to the support member, wherein in the support member and the top member are configured such that they together define a discrete chamber. The discrete chamber includes a first well region including at least one first well; a second well region including at least one second well; and a channel region including at least one channel connecting the first well region and the second well region with one another. The second region is preferably horizontally offset with respect to the first well region in a test orientation of the device.

REFERENCES:
patent: 5284753 (1994-02-01), Goodwin, Jr.
patent: 5302515 (1994-04-01), Goodwin, Jr.
patent: 5422270 (1995-06-01), Caspi
patent: 5514555 (1996-05-01), Springer et al.
patent: 5601997 (1997-02-01), Tchao
patent: 5744366 (1998-04-01), Kricka et al.
patent: 5763194 (1998-06-01), Slowiaczek et al.
patent: 5869001 (1999-02-01), Backhaus et al.
patent: 5935850 (1999-08-01), Clark et al.
patent: 5962250 (1999-10-01), Gavin et al.
patent: 6027873 (2000-02-01), Schellenberger et al.
patent: 6238874 (2001-05-01), Jarnagin et al.
patent: 6321791 (2001-11-01), Chow
patent: 6329201 (2001-12-01), Wagner et al.
patent: 6558904 (2003-05-01), Ermantraut et al.
patent: 6811968 (2004-11-01), Kirk et al.
patent: 6818403 (2004-11-01), Kirk et al.
patent: 6982171 (2006-01-01), Kim et al.
patent: WO 98/07069 (1998-02-01), None
patent: WO 00/07007 (2000-02-01), None
patent: WO 01/32827 (2001-05-01), None
patent: WO 01/34302 (2001-05-01), None
patent: WO 01/69240 (2001-09-01), None
patent: WO 01/70389 (2001-09-01), None
“Formation of Gradients of Proteins on Surfaces with Microfluidic Networks”, Caelen et al.: Langmuir (2000) vol. 16, pp. 9125-9130.
“Gradien Micropattern Immobilization of EGF to Investigate the Effect of Artificial Juxtacrine Stimulation”, Chen et al.: Biomaterials (2001) pp. 2453-2457.
“How to Prepare Tunable Planar Molecular Chemical Gradients”, Kirill Efimenko and Jan Genzer: Advanced Materials (2001) vol. 13, No. 20, pp. 1560-1563.
“Electroosmotic Properties of Microfluidic Channels Composed of Poly (Dimethylsiloxane)”, Ren et al.: Journal of Chromatography B, (2001) vol. 762, pp. 117-125.
“A Firin or Collagen Gel Assay for Tissue Cell Chemotaxis: Assessment of Fibroblast Chemotaxis to GRGDSP”, Knapp et al.:Experimental Cell Research, (1999) vol. 247, pp. 543-553.
“Development and Characterization of an ELISA assay in PDMS Microfluidic Channels”, Eteshola et al.:Sensors and Actuators (2001), vol. B72/2, pp. 129-133.
“Rapid and quantitative in vitro measurement of cellular chemotaxis and invasion”, Penno et al: Methods in Cell Science (1997) vol. 19, pp. 189-195.
“Hydrodynamic Effects on Microcapillary Motility and Chemotaxis Assays ofMethylosinus trichosporiumOB3b”, Shonnard et al.: Applied and Environmental Microbiology, (1992) vol. 58, No. 9, pp. 2737-2743.
“Effect of Cryopreservation on Chemotaxis of Lynphocytes” Abda et al.: Cryobiology (1998) vol. 36, pp. 184-193.
“Automated Real-Time Measurement of Chemotactic Cell Motility” Hadjout et al.: BioTechniques (2001) vol. 31, pp. 1130-1138.
“Transmembrane Motility Assay of Transiently Transfected Cells by Fluorescent Cell Counting and Luciferase Measurement” C. Battaglia et al., BioTechniques (2000) vol. 29, pp. 81-86.
“Experimental/Molecular Therapeutics 27” Proceedings of the American Association for Cancer Research (2001) vol. 42, p. 484.
“Motility and chemotaxis inSerpulina hyodysenteriae” Kennedy et al: Veterinary Microbiology (1996) vol. 49, pp. 21-30.
“Tumor necrosis factor-alpha decreases neutrophil chemotaxis to N-formyl-1-methionyl-1-leucy-1-phenylalanine: analysis of single cell movement.” Vollmer et al.: Journal of Leukocyte Biology (1992) vol. 52, No. 6, pp. 630-636.
“Endothelial Cell Migration and Invasiveness Are Induced by a Soluble Factor Produced by Murine Endothelioma Cells Transformed by Polyuoma Virus Middle T. Oncogene” Taraboletti et al.: Cancer Research (1993) vol. 53, pp. 3812-3816.
“Measurement of Leukocyte Motility and Chemotaxis Parameters with a Linear Under-Agarose Migration Assay” D. Lauffenburger et al.: The Journal of Immunology (1983) vol. 131, No. 2, pp. 940-947.
“Micropatterned solid-supported membranes formed by micromolding in capillaries” Andreas Janshoff et al.: Eur Biophys J. (2000) vol. 29, pp. 549-554.
“Influence of Technical Parameters on the in Vitro Motility of Equine Neutrophils in the Presence of Streptococcal Culture Supernatant” Blancquaert et al.: Veterinary Immunology and Immunopathology, (1989) vol. 23, pp. 85-101.
“Cell Movement Analysis in a Necrotactic Assay” Gruler: Blood Cells (1984) vol. 10, pp. 107-121.

Affiliated with

Also associated with

Rating

Test device and method of making same does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Test device and method of making same, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Test device and method of making same will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3753355