Surgery – Diagnostic testing – Measuring or detecting nonradioactive constituent of body...
Patent
1997-10-14
2000-03-28
Hindenburg, Max
Surgery
Diagnostic testing
Measuring or detecting nonradioactive constituent of body...
600346, 600309, 600367, 422 56, 422 58, 436165, A61B 500
Patent
active
060425431
ABSTRACT:
A device and method for determining the concentration of an analyte, particularly a chloride ion, in a liquid sample are particularly useful to screen for cystic fibrosis in an individual. In a preferred embodiment, the device takes the form of a patch comprising an absorbent material sandwiched between two liquid-impermeable layers. Chloride ions in the liquid sample complex with a chloride-detecting agent dispersed throughout the absorbent material to form a visible precipitate, preferably silver chloride. A pH indicator is also dispersed throughout the absorbent material, allowing the position of the water front to be monitored thereby permitting calculation of chloride concentration from a partially filled patch.
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Hansen Leland G.
Warwick Warren J.
Hindenburg Max
Natnithithadha Navin
Regents of the University of Minnesota
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