Test device and method for its use

Chemistry: physical processes – Physical processes – Crystallization

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Details

23230B, 232303, 422 56, 422 71, 435 4, G01N 3106, G01N 3122, G01N 3316

Patent

active

042356016

ABSTRACT:
Test device for determining a characteristic of a sample, particularly for determining substances in fluid samples. The device comprises a strip element which is composed of a material capable of transporting a developing fluid therealong by capillarity and which has a portion at a predetermined location on the strip element for receiving the test sample and portions at predetermined locations on the strip element incorporated with reagent means for providing a detectable response sensitive to the characteristic under determination. The beginning end portion of the strip element is immersed in the developing fluid which, as a result, traverses the length of the strip element, thereby promoting appropriate contact between the test sample and the reagent means resulting in the disposition of a detectable response at a predetermined location on the strip element, which response is a function of the characteristic under determination. The test device is particularly suited for performing binding assays, in particular those wherein a radioisotope is used as a label, such as radioimmunoassays.

REFERENCES:
patent: 3011874 (1961-12-01), Deutsch
patent: 3376114 (1968-04-01), Eberle
patent: 3420205 (1969-01-01), Morison
patent: 3776698 (1973-12-01), Eisentraut
patent: 3888629 (1975-06-01), Bagshawe
patent: 3893808 (1975-07-01), Campbell
patent: 3895914 (1975-07-01), Alberty et al.
patent: 3902847 (1975-09-01), Busch et al.
patent: 3915647 (1975-10-01), Wright
patent: 3932133 (1976-01-01), Ishikawa
patent: 3980437 (1976-09-01), Koshimoto et al.
patent: 4094647 (1978-06-01), Deutsch et al.

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