Chemistry: analytical and immunological testing – Biospecific ligand binding assay
Patent
1997-07-02
1999-11-23
Chin, Christopher L.
Chemistry: analytical and immunological testing
Biospecific ligand binding assay
436169, 436178, 436514, 436518, 436523, 436524, 436525, 436533, 436544, 436515, 436810, 435 792, 435 793, 435 794, 435 795, 435176, 4352871, 4352872, 4352879, 435805, 435810, 435970, 422 55, 422 56, 422 57, 422 58, G01N 3353, G01N 33566
Patent
active
059899212
ABSTRACT:
Disclosed is a test cell and a method for detection of a preselected ligand in a liquid sample such as a body fluid. The test cell includes an elongate outer casing which houses an interior permeable material capable of transporting an aqueous solution and defining a sample inlet, a test volume, and a reservoir volume. The reservoir volume is disposed in a section of the test cell spaced apart from the inlet and is filled with sorbent material. The reservoir acts to receive liquid transported along a flow path defined by the permeable material and extending from the inlet and through the test volume. In the test volume is a test site which includes a first protein having a binding site specific to a first epitope of the ligand immobilized in fluid communication with the flow path. The test site can be observed through a window of the casing.
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Charlton David E.
Miller Neal W.
Carter Wallace, Inc.
Chin Christopher L.
Do Pensee T.
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