Chemistry: analytical and immunological testing – Involving diffusion or migration of antigen or antibody
Patent
1992-12-23
1998-02-03
Spiegel, Carol A.
Chemistry: analytical and immunological testing
Involving diffusion or migration of antigen or antibody
435970, 436501, 436515, 436518, 436523, 436524, 436525, 436814, 436817, 436818, G01N 33558
Patent
active
057143897
ABSTRACT:
Disclosed is a test cell and a method for detection of a preselected ligand in a liquid sample such as a body fluid. The test cell includes an elongate outer casing which houses an interior permeable material capable of transporting an aqueous solution and defining a sample inlet, a test volume, and a reservoir volume. The reservoir volume is disposed in a section of the test cell spaced apart from the inlet and is filled with sorbent material. The reservoir acts to receive liquid transported along a flow path defined by the permeable material and extending from the inlet and through the test volume. In the test volume is a test site which includes a first protein having a binding site specific to a first epitope of the ligand immobilized in fluid communication with the flow path. The test site can be observed through a window of the casing.
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Charlton David E.
Miller Neal W.
Carter-Wallace Inc.
Spiegel Carol A.
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