Test composition, device, and method for the detection of peroxi

Details Test composition, device, and method for the detection of peroxi Test composition, device, and method for the detection of peroxi

1975-09-08

1976-10-19

Wolk, Morris O.

Chemistry: physical processes

Physical processes

Crystallization

23253TP, 252408, G01N 3316

Patent

active

039868338

ABSTRACT:
Improved test compositions, devices and methods are provided for detecting peroxidatively active substances in body fluids, excreta and the like. In the type of test compositions including an indicator capable of being oxidized in the presence of a peroxidatively active substance to provide a color change, an oxidizing agent effective to oxidize said indicator, and a potentiating agent, the improvement comprises the use as said potentiating agent of an acid salt or adduct of a compound selected from the class of compounds of the general formula ##SPC1##
Wherein R.sub.1 is hydrogen, lower alkyl, hydroxy or thiophenyl; R.sub.2 is hydrogen or lower alkyl; R.sub.3 is hydrogen or lower alkyl; R.sub.4 is hydrogen, carboxy, lower alkyl or lower alkoxy; and R.sub.5 is hydrogen or lower alkyl.

REFERENCES:
patent: 3290117 (1966-12-01), Adams, Jr. et al.
patent: 3506404 (1970-04-01), Evans et al.
patent: 3654179 (1972-04-01), Bauer
patent: 3667915 (1972-06-01), Klein
patent: 3853472 (1974-12-01), Rittersdorf et al.
Gradwohl's Clinical Laboratory Methods and Diagnosis, 7th ed., vol. 2, Mosby & Co., St. Louis, (1970), pp. 1873-1874 relied upon.
Merck Index, 8th Ed., pp. 906-907, (1968).

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