Test combination and method of detecting fibrin monomers in bloo

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving blood clotting factor

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436 63, 436 69, 424116, 424121, 424122, 514422, 548518, G01N 3368, G01N 3386

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049606948

ABSTRACT:
A test reagent for detecting fibrin monomers in blood, comprises an antibiotic of a pyrrole amidine series as a precipitant, introduced in a buffer solution. A method of detecting fibrin monomers in blood, comprises the steps of mixing venous blood with an anticoagulant, centrifuging the mixture of the venous blood with the anticoagulant, removing a citrate plasma, using an antibiotic of a pyrrole amidine series as a precipitant, and evaluating a precipitation reaction which takes place thereby.

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Patel, D., "Antibiotic-DNA Interactions: Intermolecular Nuclear Overhauser Effects in the Netropsin-d(C-G-C-G-A-A-T-T-C-G-C-G) Complex in Solution", Proc. Natl. Acad. Sci., U.S.A., vol. 79, pp. 6424-6428, Nov. 1982.
Biological Abstract 85:13421.

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