Test carrier with separation means for analyzing a sample fluid

Details Test carrier with separation means for analyzing a sample fluid Test carrier with separation means for analyzing a sample fluid

1991-02-12

1993-02-23

Johnston, Jill A.

Chemistry: analytical and immunological testing

Optical result

With reagent in absorbent or bibulous substrate

436169, 436164, 436165, 422 55, 422 56, 422 58, 435805, 435970, G01N 2177, G01N 3122

Patent

active

051889668

ABSTRACT:
Test carrier for analyzing a sample fluid with several test layers which form a sample fluid transport path and contain a reagent system which reacts with the sample fluid to produce a detectable signal. The test carrier includes a reservoir layer of absorbent material, a detection layer arranged in the fluid transport path downstream the reservoir layer, in which a detectable signal is formed, and a separating layer arranged between the reservoir layer and the detection layer. The separating layer makes a two-step process possible. Fluid contact between the reservoir layer and the detection layer arises only with pressure loading of the layer assembly of the reservoir layer, separating layer and detection layer. A more uniform optical detection signal, and consequently better accuracy, can be achieved because the separating layer is made up of a hydrophilic material, wich is in the form of a lattice-shaped structure, in which the mean width of the lattice openings is more than 0.05 mm, and the threads from which the lattice-shaped structure is formed are multi-filament.

REFERENCES:
patent: 3582537 (1971-06-01), Perreault
patent: 3723064 (1973-03-01), Liotta
patent: 4292272 (1981-09-01), Kitajima et al.
patent: 4780280 (1988-10-01), Berger et al.
patent: 4816224 (1989-03-01), Vogel et al.
patent: 4839297 (1989-06-01), Freitag et al.
patent: 4876067 (1989-10-01), Deneke et al.

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