Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving blood clotting factor
Patent
1994-05-06
1995-05-23
Wityshyn, Michael G.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving blood clotting factor
435212, 422 56, 530381, 530384, C12Q 156, C12N 948, G01N 3122
Patent
active
054181410
ABSTRACT:
Test articles comprise a solid phase membrane having dry thromboplastin immobilized thereon or within. The thromboplastin is substantially free from substances which might cause aberrant functioning intermediate transition states as the thromboplastin is rehydrated with liquid sample. Coagulation neutral agents which facilitate rehydration of the dry thromboplastin are also provided on the solid phase membrane.
REFERENCES:
patent: 4416812 (1983-11-01), Becker et al.
patent: 4774192 (1988-09-01), Terminiello
patent: 5059525 (1991-10-01), Bartl
patent: 5110730 (1992-05-01), Edington et al.
patent: 5254350 (1993-10-01), Barrow
patent: 5270451 (1993-12-01), Hawkins
Tripodi A., Recombinant Tissue Factor as Substitute . . . Thrombosis & Haemostasis 67(1) 42-45 1992.
Hawkins P., Prothrombin Time Reagents Prepared . . . Clinical Hemostasis Review Apr. 1992.
Hawkins et al., "Prothrombin Time Reagents Prepared Using Recombinant Human Tissue Factor Produced in E. Coli", Clinical Hemostasis Review, Apr. 1992.
T. B. L. Kirkwood, "Calibration of Reference Thromboplastins and Standardisation of the Prothrombin Time Ratio", Thromb Haemostas 49(3):238-244 (1983).
S. Krishnaswamy, "The Interaction of Human Factor VIIa with Tissue Factor", J. Biol. Chem. 267(33):24696-24706 (1992).
Y. Nemerson, "Tissue Factor and Hemostasis", Blood 71(1):1-8 (1988).
J. D. Rawn, Biochemistry, Neil Patterson Publishers, pp. 219-232, Burlington N.C. 1989.
Shigematsu et al., "Expression of Human Soluble Tissue Factor in Yeast and Enzymatic Properties of Its Complex with Fator VIIa", J. Biol. Chem. 267(30):21329-21337 (1992).
Tripodi et al., "Recombinant Tissue Factor as Subsitute for Conventional Thromboplastin in the Prothrombin Time Test", Thrombosis and Haemostasis 67(1):42-45 (1992).
Meyer Benjamin G.
Sharma Sameer
Zweig Stephen E.
Avocet Medical, Inc.
Gitomer Ralph
Wityshyn Michael G.
LandOfFree
Test articles for performing dry reagent prothrombin time assays does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Test articles for performing dry reagent prothrombin time assays, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Test articles for performing dry reagent prothrombin time assays will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2139994