Tertiary and secondary amines as alpha-2 antagonists and seroton

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514415, 514416, 514417, 514418, 5142242, 5142305, 514249, 514259, 514248, 514307, 514311, 514312, 514367, 514373, 514375, 514379, 514394, 514434, 514443, 514454, 514457, 514439, 514463, 514469, 514470, 514655, 514361, 548454, 548472, 548475, 548481, 548482, 548484, 548485, 548486, 548491, 548503, 548126, 548164, 548173, 548169, 548179, 548207, 548209, 548217, 548221, 548241, 5483051, 5483611, 5483615, 544 50, 544 52, 544 90, 544 92, 544105, 544235, 544237, 544283, 544286, 544353, 544354, 546141, 546149, 546

Patent

active

052887499

ABSTRACT:
The present invention provides tertiary and secondary amine compounds of the formula ##STR1## and the pharmaceutically acceptable salts thereof which are antagonists for alpha-2 adrenoreceptors and which inhibit serotonin (5-hydroxytryptamine, 5-HT) uptake.

REFERENCES:
patent: 4564628 (1986-01-01), Horn
patent: 4722933 (1988-02-01), Horn
patent: 4968679 (1990-11-01), Junge et al.
patent: 5086074 (1992-02-01), DeBernardis et al.
patent: 5118704 (1992-06-01), Minaskanian et al.
patent: 5140040 (1992-08-01), DeBernardis et al.

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