Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...
Patent
1975-03-24
1976-10-26
Goldberg, Jerome D.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Recombinant or stably-transformed bacterium encoding one or...
A61K 31165
Patent
active
039884732
ABSTRACT:
Tertiary-alkylamino-lower acyl-xylidides have unusually long lasting local anaesthetic effect or high local anaesthetic activity while also having a satisfactory low level of tissue irritation and a satisfactory low acute toxicity. Combinations of such local anaesthetics with the biotoxins tetrodotoxin or saxitoxin are disclosed. Novel tertiary alkyl secondary amines, and methods for preparing such local anaesthetics and amines are also disclosed.
REFERENCES:
Epstein, et al., J. of Am. Pharm. Assn., 49, pp. 80-82 (1960).
Lofgren, et al., Acta. Chem. Scan. 11, pp. 1724-1737 (1957).
Adams Herbert J. F.
Anderson Jon C.
Blair, Jr. Murray R.
Di Rubio Robert L.
Takman Bertil H.
Astra Pharmaceutical Products Inc.
Goldberg Jerome D.
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