Terphenyl guanidines as β-secretase inhibitors

Details Terphenyl guanidines as β-secretase inhibitors Terphenyl guanidines as β-secretase inhibitors

2007-10-23

2007-10-23

Davis, Brian (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

C514S634000

Reexamination Certificate

active

11352887

ABSTRACT:
The present invention provides terphenyl guanidine compounds of formula IThe present invention also provides methods for the use thereof to inhibit β-secretase (BACE) and treat β-amyloid deposits and neurofibrillary tangles.

REFERENCES:
patent: 6399824 (2002-06-01), Hofmeister et al.
patent: WO 01/87829 (2001-11-01), None

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