Terminally modified tri-, tetra- and pentapeptide anaphylatoxin

Details Terminally modified tri-, tetra- and pentapeptide anaphylatoxin Terminally modified tri-, tetra- and pentapeptide anaphylatoxin

1991-06-04

1993-03-02

Cashion, Jr., Merrell C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 17, 514 19, 530328, 530329, 530330, 530331, 930 20, 930 21, A61K 3700, C07K 500

Patent

active

051909227

ABSTRACT:
Oligopeptide compounds or oligopeptide analogue compounds of the formula A-B-D-E-G-J-L are ligands for the anaphylatoxin receptor and are useful in the treatment of inflammatory disease states. Also disclosed are anaphylatoxin receptor ligand compositions and a method for modulating anaphylatoxin activity.

REFERENCES:
Eur. J. Immun. (1990) Kohl et al. vol. 20 1463-1468.

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