Tenascin-C isoform as marker for neoplasias

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

Reexamination Certificate

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C530S387300, C530S387700, C530S388100, C530S388800, C530S388850, C530S391100, C530S391300, C435S007100, C424S130100

Reexamination Certificate

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07109301

ABSTRACT:
Diagnostic method for the identification of human neoplasias based on the determination of the CTN-C isoform of TN-C, fragments antibodies and their conjugates used in said method, and their therapeutic use.

REFERENCES:
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Jain (Sci. Am., 1994, 271:58-65).
Curti (Crit. Rev. in Oncology/Hematology, 1993, 14-29-39).
Johnston and Thorpe (Immunochemistry in Practice, Blackwell Scientific Publications, Oxford, 1987, pp. 49-50).
Meiners et al (J. Neuroscience, 1999, 19:8443-8453).
Murphy-Ullrich et al (J. Cell. Biol., 1991, 115:1127-1136).
Klausner,(Biotechnology, 1986, 4:1042-1043).

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