Template synthesis of macrocyclic catecholamide complexes

Organic compounds -- part of the class 532-570 series – Organic compounds – Unsubstituted hydrocarbyl chain between the ring and the -c-...

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514184, 514185, 514186, 422 2, 422 9, 330299, C07D48718, A61K 31395

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049392549

ABSTRACT:
A method is provided for a high yield template synthesis of macrocyclic catecholamide ligands.

REFERENCES:
patent: 4702998 (1987-10-01), Tanaka et al.
Hosseini, M. W. et al., "Synthesis of Cage-Type Iron Sequestering Agents", XI International Symposium on Macrocyclic Chemistry, Florence, Italy, Sep. 1-4, 1986.
Kiggen, W. et al., Angew. Chem Inter. Ed. Eng. (1984), 23, 714.
McMurry, T. J. et al., "Macrobicyclic Iron (III) Sequestering Agents", J. Am. Chem. Soc., 109, 7196 (1987).
Rodgers, S. J. et al., "Ferric Iron Sequestering Agents", 15, Synthesis, Solution Chemistry, and Electrochemistry of a New Cationic Analogue of Enterobactin, Inorganic Chem., 26, 1622 (1987).
McMurry, T. J. et al., "Template and Stepwise Syntheses of a Macrobicyclic Catechoylamide Ferric Iron Sequestering Agent", JACS, 109, 3451 (1987).

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