Template imprinted materials by RFGD plasma deposition

Details Template imprinted materials by RFGD plasma deposition Template imprinted materials by RFGD plasma deposition

1999-04-15

2000-10-17

Nguyen, Dinh X.

Surgery

Miscellaneous

Methods

623 1111, 623 2375, 623 2376, 427 224, 427447, A61B 1900

Patent

active

06131580&

ABSTRACT:
Template-imprinted structures 10 are provided having at least one template-imprinted surface 12 defining indentations 14 that are capable of specifically binding cells and/or molecules, such as macromolecules including proteins, peptides and nucleic acids. Presently preferred embodiments of the template-imprinted structures include medical prostheses, such as artificial joints and heart valves, having surface indentations that specifically bind proteins and/or cells that enhance the biocompatibility of the prosthesis, thereby making it less likely that the prosthesis will be rejected by the body. Methods are also provided for making the template-imprinted structures of the present invention.

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patent: 5153072 (1992-10-01), Ratner et al.
patent: 5429735 (1995-07-01), Johnson et al.
Flam, F., "Molecular Imprints Make a Mark", Science, vol. 263, pp. 1221-1222, Mar. 4, 1994.
Srauss, E., "New Ways to Probe the Molecules of Life," Science, vol. 282, pp. 1407-1407, Nov. 20, 1998.

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