Temperature stable crystalline di(1-methyl-2-pyrralidinone) and

Details Temperature stable crystalline di(1-methyl-2-pyrralidinone) and Temperature stable crystalline di(1-methyl-2-pyrralidinone) and

1986-01-10

1987-07-14

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D50146

Patent

active

046803890

ABSTRACT:
Crystalline adducts of 7-[(Z)-2-methoxyimino-2-(2-aminothiazol-4-yl)acetamido-3-[(1-methyl-1-pyrr olidinium)methyl]-3-cephem-4-carboxylate selected from the group consisting of the di(1-methyl-2-pyrrolidinone) adduct and the di(N-formyl pyrrolidine) adduct and salt complexes thereof have been found to be stable at even high temperatures. The crystalline adducts are prepared by forming an admixture of adducting agents, zwitterions and seed adduct crystals and inducing crystallization followed by isolating the crystals. A process for preparing adduct salt complexes is also disclosed. Crystalline zwitterion can be formed by slurrying the adducts in a solvent which removes the adducting agents.

REFERENCES:
patent: 4318852 (1982-03-01), Heitman et al.
patent: 4406899 (1983-09-01), Aburaki et al.

Affiliated with

Also associated with

Rating

Temperature stable crystalline di(1-methyl-2-pyrralidinone) and does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Temperature stable crystalline di(1-methyl-2-pyrralidinone) and , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Temperature stable crystalline di(1-methyl-2-pyrralidinone) and will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1428541