Temperature-controlled active agent dispenser

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Web – sheet or filament bases; compositions of bandages; or...

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424416, 424449, 424484, 424486, 424487, A61F 1302, A61K 914

Patent

active

048308552

ABSTRACT:
Temperature-controlled diffusional active agent dispensers that use a side-chain crystallizable polymer in a form that is not free to flow above its melt temperature as a rate-controlling matrix are disclosed. The polymer may be crosslinked to render it nonflowable, be supported, or grafted to a permeable support. Elements that facilitate or permit heating by radiation or electrical conductance/inductance may be included in the dispenser. At temperatures below the melt temperature of the polymer, the polymer is substantially impermeable to the agent. At tempertures at or above the melt temperature the polymer is substantially permeable to the agent.

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