Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1993-05-13
1997-12-09
Campbell, Eggerton A.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 911, C12Q 168, C12P 1934
Patent
active
056959320
ABSTRACT:
Method and compositions are provided for the determination of telomere length and telomerase activity, as well as the ability to inhibit telomerase activity in the treatment of proliferative diseases. Particularly, primers are elongated under conditions which minimize interference from other genomic sequences, so as to obtain accurate determinations of telomeric length or telomerase activity. In addition, compositions are provided for intracellular inhibition of telomerase activity and means are shown for slowing the loss of telomeric repeats in aging cells.
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Blackburn Elizabeth H.
McEachern Michael J.
Shay Jerry
West Michael D.
Wright Woodring
Campbell Eggerton A.
The Regents of the University of California
University of Texas System
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