Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 25 or more amino acid residues in defined sequence
Reexamination Certificate
2004-09-28
2010-02-09
Lukton, David (Department: 1654)
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
25 or more amino acid residues in defined sequence
C530S300000, C530S345000, C562S571000, C562S573000, C514S002600
Reexamination Certificate
active
07659365
ABSTRACT:
The invention relates to novel materials based on biodegradable homopolyamino acids and which can be used for the vectorization of (an) active ingredient(s) (AI). The invention also relates to novel pharmaceutical, cosmetic, dietetic or phytosanitaty compositions based on homopolyamino acids. The invention can produce a novel polymer raw material which can be used for the vectoiization of Al that can optimally be: biocompatible, biodegradable, capable of becoming easily associated with a large number of active ingredients or solubilizing them and releasing the active ingredients in vivo. According to the present invention, which primarily relates to linear homopolyamino acids having aspartic or glutamic units and whose attachments can include hydrophobic groups having 8-30 carbon atoms. The homopolymers are amphiphilic and anionic and can easily be transformed at low cost into particles for the vectorization of active ingredients. The particles can form stable aqueous colloidal suspensions.
REFERENCES:
patent: 2680749 (1954-06-01), Cawley et al.
patent: 3536672 (1970-10-01), Fujimoto et al.
patent: 4126628 (1978-11-01), Paquet
patent: 4321253 (1982-03-01), Beatty
patent: 4351337 (1982-09-01), Sidman
patent: 4443549 (1984-04-01), Sadowski
patent: 4450150 (1984-05-01), Sidman
patent: 4600526 (1986-07-01), Gallot et al.
patent: 4615697 (1986-10-01), Robinson
patent: 4652441 (1987-03-01), Okada et al.
patent: 4661345 (1987-04-01), Tuomanen
patent: 4748023 (1988-05-01), Tamas et al.
patent: 4766106 (1988-08-01), Katre et al.
patent: 4835293 (1989-05-01), Bhatia
patent: 4888398 (1989-12-01), Bichon et al.
patent: 4892733 (1990-01-01), Bichon et al.
patent: 4894240 (1990-01-01), Geoghegan et al.
patent: 4904479 (1990-02-01), Illum
patent: 4976968 (1990-12-01), Steiner
patent: 5023349 (1991-06-01), Bhatia
patent: 5084278 (1992-01-01), Mehta
patent: 5102872 (1992-04-01), Singh et al.
patent: 5204108 (1993-04-01), Illum
patent: 5286495 (1994-02-01), Batich et al.
patent: 5286497 (1994-02-01), Hendrickson et al.
patent: 5399331 (1995-03-01), Loughrey et al.
patent: 5449513 (1995-09-01), Yokoyama et al.
patent: 5510103 (1996-04-01), Yokoyama et al.
patent: 5514380 (1996-05-01), Song et al.
patent: 5534241 (1996-07-01), Torchilin et al.
patent: 5589455 (1996-12-01), Woo
patent: 5609872 (1997-03-01), Ahlborg et al.
patent: 5656722 (1997-08-01), Dorschug
patent: 5780579 (1998-07-01), Soula et al.
patent: 5834422 (1998-11-01), Balschmidt
patent: 5852109 (1998-12-01), Makino et al.
patent: 5863900 (1999-01-01), Russell-Jones
patent: 5869703 (1999-02-01), Kim et al.
patent: 5872210 (1999-02-01), Medabalimi
patent: 5876969 (1999-03-01), Fleer et al.
patent: 5904936 (1999-05-01), Huille et al.
patent: 5981761 (1999-11-01), Chou et al.
patent: 6143314 (2000-11-01), Chandrashekar et al.
patent: 6153193 (2000-11-01), Kabanov et al.
patent: 6180141 (2001-01-01), Lemercier et al.
patent: 6193953 (2001-02-01), Lohrmann et al.
patent: 6197535 (2001-03-01), Bandyopadhyay et al.
patent: 6201072 (2001-03-01), Rathi et al.
patent: 6235282 (2001-05-01), Riviere et al.
patent: 6284267 (2001-09-01), Aneja
patent: 6309633 (2001-10-01), Ekwuribe et al.
patent: 6313095 (2001-11-01), Adams et al.
patent: 6313260 (2001-11-01), Gruning et al.
patent: 6320017 (2001-11-01), Ansell
patent: 6500448 (2002-12-01), Johnson et al.
patent: 6576254 (2003-06-01), Uchegbu
patent: 6630171 (2003-10-01), Huille et al.
patent: 6933269 (2005-08-01), Jordan, IV et al.
patent: 6946146 (2005-09-01), Mulye
patent: 7030155 (2006-04-01), Lambert et al.
patent: 7226618 (2007-06-01), Touraud et al.
patent: 7261875 (2007-08-01), Li et al.
patent: 7270832 (2007-09-01), Bryson et al.
patent: 2001/0000510 (2001-04-01), Sakurai et al.
patent: 2002/0068085 (2002-06-01), Rudnic et al.
patent: 2003/0133980 (2003-07-01), Costantino et al.
patent: 2004/0038885 (2004-02-01), Bryson et al.
patent: 2004/0063628 (2004-04-01), Piccariello et al.
patent: 2004/0071716 (2004-04-01), Jansen et al.
patent: 2004/0175424 (2004-09-01), Castan et al.
patent: 2005/0158392 (2005-07-01), Kim et al.
patent: 2006/0099264 (2006-05-01), Chan et al.
patent: 2007/0010652 (2007-01-01), Angot et al.
patent: 2007/0160568 (2007-07-01), Angot et al.
patent: 2007/0178126 (2007-08-01), Angot et al.
patent: 2007/0190162 (2007-08-01), Caillol et al.
patent: 2007/0196497 (2007-08-01), Pouliquen et al.
patent: 2007/0248686 (2007-10-01), Touraud et al.
patent: 2007/0254828 (2007-11-01), Dubreucq et al.
patent: 2007/0265192 (2007-11-01), Soula et al.
patent: 2008/0014250 (2008-01-01), Soula et al.
patent: 2008/0015332 (2008-01-01), Bryson et al.
patent: 2009/0012028 (2009-01-01), Chan et al.
patent: 2009/0110742 (2009-04-01), Constancis et al.
patent: 2068366 (1992-11-01), None
patent: 0 198 769 (1986-10-01), None
patent: 0 179 023 (1991-01-01), None
patent: 0 583 955 (1994-02-01), None
patent: 0 601 508 (1994-06-01), None
patent: 0 721 776 (1996-07-01), None
patent: 0 734 720 (1996-10-01), None
patent: 0 963 758 (1999-12-01), None
patent: 2 732 218 (1996-10-01), None
patent: 2 746 035 (1997-09-01), None
patent: 2 801 226 (2001-05-01), None
patent: 2 838 964 (2003-10-01), None
patent: 2 860 516 (2003-10-01), None
patent: 2 840 614 (2003-12-01), None
patent: 2 843 117 (2004-02-01), None
patent: 2 855 521 (2004-12-01), None
patent: 2 873 040 (2006-01-01), None
patent: 966 760 (1964-08-01), None
patent: 1 024 393 (1966-03-01), None
patent: 1 202 765 (1970-08-01), None
patent: 2 041 517 (1980-09-01), None
patent: 2 240 547 (1991-08-01), None
patent: WO 87/002219 (1987-04-01), None
patent: WO 87/003891 (1987-07-01), None
patent: WO 88/001213 (1988-02-01), None
patent: WO 88/007078 (1988-09-01), None
patent: WO 89/008449 (1989-09-01), None
patent: WO 91/006286 (1991-05-01), None
patent: WO 91/006287 (1991-05-01), None
patent: WO 96/029991 (1996-10-01), None
patent: WO 96/040279 (1996-12-01), None
patent: WO 97/002810 (1997-01-01), None
patent: WO 97/034584 (1997-09-01), None
patent: WO 98/011874 (1998-03-01), None
patent: WO 99/018142 (1999-04-01), None
patent: WO-99/61512 (1999-12-01), None
patent: WO 00/018821 (2000-04-01), None
patent: WO 00/030618 (2000-06-01), None
patent: WO 85/002092 (2000-06-01), None
patent: WO 00/071163 (2000-11-01), None
patent: WO-00/78791 (2000-12-01), None
patent: WO 01/037809 (2001-05-01), None
patent: WO 02/028251 (2002-04-01), None
patent: WO 02/028521 (2002-04-01), None
patent: WO 02/039984 (2002-05-01), None
patent: WO-02/098951 (2002-12-01), None
patent: WO 02/098952 (2002-12-01), None
patent: WO 03/002096 (2003-01-01), None
patent: WO 03/013467 (2003-02-01), None
patent: WO 03/104303 (2003-12-01), None
patent: WO 2004/013206 (2004-02-01), None
patent: WO 2004/060968 (2004-07-01), None
patent: WO 2004/108796 (2004-12-01), None
patent: WO 2005/033181 (2005-04-01), None
patent: WO 2005/051416 (2005-06-01), None
patent: WO 2006/016078 (2006-02-01), None
patent: WO 2007/034320 (2007-03-01), None
patent: WO 2007/116143 (2007-10-01), None
International Search Report mailed Apr. 18, 2005, for No. PCT/FR2004/050465,with English translation.
French Search Report dated Mar. 29, 2004, for No. FR 03-50641.
International Search Report PCT/FR2004/050465, filed Apr. 5, 2005.
Akiyoshi et al., Self-assembled hydrogel nanoparticle of cholesterol-bearing pullulan as a carrier of protein drugs: Complexation and stabilization of insulin, J. Controlled Release 54: 313-320(1998).
Ed. R. Arshady, Micropsheres, Microcapsules and Liposomes; vol. 1 Preparation and Chemical applications, Citrus Books 1999, London.
Ed. J. Senior and M. Radomsky,Sustained-Release Injectable Products, Interpharm Press 2000, Denver.
Ed. J. Kreuter,Colloidal Drug Delivery Systems, Drugs and the Pharmaceutical Sciences, vol. 66, Marcel Dekker, Inc. 1994, Wilmington.
Ed. D.L. Wise, Handbook of Pharmaceutical Controlled Release Technology, Marcel Dekker, Inc. 2000, New York.
Fuller et al., A procedure for the facile synthesis of amino-acid N-carboxyanhydrides, Biopolymers 15: 1869-71 (1976).
Krichekdorf, H.R., Alpha-amino acid N-carboxy anhydride and related heterocycles, Spring Verlag (1987) Berlin.
In th
Breyne Olivier
Chan You-Ping
Soula Gerard
Soula Rémi
Flamel Technologies
Lukton David
Patton & Boggs LLP
LandOfFree
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