Technetium-99m labelled peptides for imaging inflammation

Details Technetium-99m labelled peptides for imaging inflammation Technetium-99m labelled peptides for imaging inflammation

1995-06-07

1998-01-27

Kight, John

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

In an organic compound

424 111, 424 165, 534 10, 534 14, 530300, A61K 5100, A61M 3614

Patent

active

057119317

ABSTRACT:
This invention relates to radiolabeled peptides and methods for producing such peptides. Specifically, the invention relates to technetium-99m (Tc-99m) labeled leukocyte-binding peptides, methods and kits for making such peptides, and methods for using such peptides to image sites of infection and inflammation in a mammalian body.

REFERENCES:
patent: 4986979 (1991-01-01), Morgan, Jr. et al.
patent: 5277892 (1994-01-01), Rhodes
patent: 5376356 (1994-12-01), Morgan, Jr.
patent: 5443815 (1995-08-01), Dean et al.
Moyer et al (1996). J. Nucl. Med, vol. 37, No. 4, pp. 673-679, "Technetium-99m White Blood Cell Specific Imaging Agent Developed from Platelet Factor 4 to Detect Infection."

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